Author: Michael J. Rosenberg
About the book:
Apply adaptive research to improve results in drug development
The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently, with a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts,priciples, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development.
Chapters explore such subjects as:
The adaptive concept
Design and operational adaptations
Sample-size reestimation
Agile clinical development
Safety and dose finding
Statitics in adaptive research, including frequentist and Bayesian approches
Data management technologies
The future of clinical development
