Drugs which are unstable in solution have, until today, been packaged in powder or lyophilizate form in
glass bottles. They then need to be reconstituted at the patient's bedside, or in the hospital pharmacy,
in aseptic conditions. There are many errors and accidents linked to reconstitutions which pose a real
risk for patients and healthcare personnel: errors with diluents, dosage errors, needle stick injuries,
contamination, etc. To reduce these risks, Technoflex has developed Dual-Mix®, an innovative primary
packaging which meets three challenges: storing the drug to be reconstituted, making its reconstitution
secure and ensuring the safety of healthcare staff and the patient.
Dual-Mix® is a patented bag which contains a medicine in powder/lyophilizate form and the associated
diluent in the same dual-chamber primary packaging. It facilitates and makes safe the packaging of very
unstable molecules which need to be reconstituted just before administration to the patient. Designed
in Inerta® polypropylene, the material in contact with the main active ingredient and the diluent is fully
compliant with European and American pharmacopoeias.
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